Inventory of Guidelines

ISLH is committed to ensuring an up to date inventory of guidelines that support the Hematology Laboratory community. You may view our inventory of guidelines by selecting a category/topic below. Please note that the search/sort options will only include guidelines for the currently selected category/topic.

Pre-Analytical

Guideline Title Organization Year Action

International normalized ratio and activated partial thromboplastin time testing

2022

View

International Council for Standardization in Haematology (ICSH) recommendations for processing of blood samples for coagulation testing

ICSH

2021

View

Recommendations for estimating measurement uncertainty in medical laboratories (ISO 15189 and ISO 20914)

SIPMeL

2021

View

Recommendations for the measurement of thrombin generation: Communication from the ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies

ISTH/SSC

2021

View

Optimal Testing: AACC's Guide to Lab Test Utilization

AACC

2020

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Guidelines on the laboratory aspects of assays used in haemostasis and thrombosis

BSH

2020

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Strategies for eliciting and synthesizing evidence for guidelines in rare diseases

BMC

2019

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Reversal of direct oral anticoagulants: Guidance from the Anticoagulation Forum

Anticoagulation Forum

2019

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Croatian Society of Medical Biochemistry and Laboratory Medicine: National recommendations for blood collection, processing, performance and reporting of results for coagulation screening assays prothrombin time, activated partial thromboplastin time, thrombin time, fibrinogen and D-dimer.

Croatian Society of Medical Biochemistry and Laboratory Medicine

2019

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Joint EFLM-COLABIOCLI Recommendation for venous blood sampling

EFLM-COLABIOCLI

2018

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Hematopathology

Guideline Title Organization Year Action

Practice guidelines for BRCA1/2 tumour testing in ovarian cancer

CCMG and Canadian Association of Pathologists

2022

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Laboratory Detection and Initial Diagnosis of Monoclonal Gammopathies

CAP

2021

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Coagulation

Guideline Title Organization Year Action

Added value of antiphosphatidylserine/prothrombin antibodies in the workup of thrombotic antiphospholipid syndrome: Communication from the ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies

ISTH SSC

2022

View

Laboratory coagulation tests and recombinant porcine factor VIII: A United Kingdom Haemophilia Centre Doctors’ Organisation guideline

United Kingdom Haemophilia Centre Doctors’ Organisation

2022

View

Heparin Resistance — Clinical Perspectives and Management Strategies

2021

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Recommendations for clinical laboratory testing for protein S deficiency: Communication from the SSC committee plasma coagulation inhibitors of the ISTH

ISTH SSC

2021

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2021 Update of the International Council for Standardization in Haematology Recommendations for Laboratory Measurement of Direct Oral Anticoagulant

ICSH

2021

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Lupus anticoagulant detection in anticoagulated patients. Guidance from the Scientific and Standardization Committee for lupus anticoagulant/antiphospholipid antibodies of the International Society on Thrombosis and Haemostasis

ISTH SSC

2020

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Guidance from the Scientific and Standardization Committee for lupus anticoagulant/antiphospholipid antibodies of the International Society on Thrombosis and Haemostasis

ISTH SSC

2020

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Update of the guidelines for lupus anticoagulant detection and interpretation

ISTH SSC

2020

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Recommendations for clinical laboratory testing for protein C deficiency, for the subcommittee on plasma coagulation inhibitors of the ISTH

ISTH SSC

2020

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Recommendations for clinical laboratory testing of activated protein C resistance; communication from the SSC of the ISTH

ISTH SSC

2019

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International Council for Standardization in Haematology (ICSH) Recommendations for Laboratory Measurement of Direct Oral Anticoagulants

ICSH

2018

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Laboratory criteria for antiphospholipid syndrome: communication from the SSC of the ISTH

ISTH SSC

2018

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European evidence-based recommendations for diagnosis and treatment of paediatric antiphospholipid syndrome: the SHARE initiative

NIH

2017

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Activated Partial Thromboplastin Time Monitoring of Unfractionated Heparin Therapy: Issues and Recommendations

NIH

2017

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Position Paper on laboratory testing for patients on direct oral anticoagulants. A Consensus Document from the SISET, FCSA, SIBioC and SIPMeL

Blood Transfusion

2017

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Internal quality control practices in coagulation laboratories: recommendations based on a patterns-of-practice survey

IQMH

2015

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Diagnosis of inherited platelet function disorders: Guidance from the SSC of the ISTH

ISTH

2015

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Testing for antiphospholipid antibodies with solid phase assays: guidance from the SSC of the ISTH

ISTH

2014

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Validation of hemostasis and coagulation assays: recommendations and guidelines

Independent authors (STH)

2014

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The diagnosis and management of von Willebrand disease: a United Kingdom Haemophilia Centre Doctors Organization guideline approved by the British Committee for Standards in Haematology

UKHCDO / BCSH

2014

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Hemoglobinopathies and Red Cell Disorders

Guideline Title Organization Year Action

American Society of Hematology 2020 guidelines for sickle cell disease: transfusion support

ASH

2020

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American Society of Hematology 2020 guidelines for sickle cell disease: management of acute and chronic pain

ASH

2020

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ICSH recommendations for assessing automated high-performance liquid chromatography and capillary electrophoresis equipment for the quantitation of HbA2

ICSH

2015

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ICSH guidelines for the laboratory diagnosis of nonimmune hereditary red cell membrane disorders

ICSH

2015

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ICSH recommendations for identification, diagnostic value, and quantitation of schistocytes

ICSH

2011

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ICSH recommendations for identification, diagnostic value, and quantitation of schistocytes

ICSH

2011

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Cellular Analysis

Guideline Title Organization Year Action

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.

WHO

2016

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Initial Diagnostic Workup of Acute Leukemia: Guideline From the College of American Pathologists and the American Society of Hematology

CAP

2016

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ICSH recommendations for the standardization of nomenclature and grading of peripheral blood cell morphological features

ICSH

2015

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ICSH guidelines for the standardization of bone marrow immunohistochemistry

ICSH

2015

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ICSH guidelines for the evaluation of blood cell analyzers including those used for differential leucocyte and reticulocyte counting

ICSH

2014

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ICSH guidelines for the verification and performance of automated cell counters for body fluids

ICSH

2014

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Flow Cytometry

Guideline Title Organization Year Action

Consensus recommendations on flow cytometry for the assessment of inherited and acquired disorders of platelet number and function: Communication from the ISTH SSC Subcommittee on Platelet Physiology

ISTH SSC

2021

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ICCS/ESCCA consensus guidelines to detect GPI-deficient cells in paroxysmal nocturnal hemoglobinuria (PNH) and related disorders

ICCS/ESCCA

2018

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Minimal Residual Disease and Childhood Leukemia: Standard of Care Recommendations From the Pediatric Oncology Group of Ontario MRD Working Group

PBC

2016

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Immunophenotyping of acute leukemia and lymphoproliferative disorders: a consensus proposal of the European LeukemiaNet Work Package 10

ESCCA

2011

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COVID

Guideline Title Organization Year Action

A systematic review of biomarkers among hospitalized patients with COVID-19 predictive of venous thromboembolism: A communication from the Predictive and Diagnostic Variables Scientific and Standardization Committee of the ISTH

ISTH SSC

2022

View

Good practice statements for antithrombotic therapy in the management of COVID-19: Guidance from the SSC of the ISTH

ISTH SSC

2022

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Antithrombotic agents in patients with COVID-19

CMAJ

2022

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Characteristics of VITT antibodies in patients vaccinated with Ad26.COV2.S

2022

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COVID-Inflicted Coagulopathy: Expert Consensus on Management with Novel Oral Anticoagulants in India

2021

View

Clinical Practice Guideline Summary: Recommended Drugs and Biologics in Adult Patients with COVID-19

Ontario Science Table

2022

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Alert to Health Care Professionals about a potential drug-drug interaction between Paxlovid and anticoagulants

Thrombosis Canada

2022

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WHO recommends two new drugs to treat COVID-19

WHO

2022

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The COVID-19 Treatment Guidelines Panel's Statement on Anticoagulation in Hospitalized Patients With COVID-19

NIH

2022

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Evidence-Based Recommendations on the Use of Anti-SARS-CoV-2 Monoclonal Antibodies (Casirivimab + Imdevimab, and Sotrovimab) for Adults in Ontario

Ontario Science Table

2021

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Vaccine-induced immune thrombotic thrombocytopenia (VITT) - update on diagnosis and management considering different resources

2021

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VITT, COVID-19 and the Expert Haematology Panel: The story of how the UK responded to emerging cases of vaccine-induced immune thrombocytopenia and thrombosis during the vaccination programme

UK Expert Haematology Panel

2021

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Toxic Effects from Ivermectin Use Associated with Prevention and Treatment of Covid-19

ADD

2021

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Evidence-Based Use of Therapeutics for Ambulatory Patients with COVID-19

Ontario Science Table

2021

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Clinical Practice Guideline Summary: Recommended Drugs and Biologics in Adult Patients with COVID-19

Ontario Science Table

2021

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COVID-19 rapid guideline: vaccine-induced immune thrombocytopenia and thrombosis (VITT)

NICE

2021

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Guidance for clinical case management of thrombosis with thrombocytopenia syndrome(TTS) following vaccination to prevent coronavirus disease (COVID-19)

WHO

2021

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COVID-19 Vaccine AstraZeneca: benefits still outweigh the risks despite possible link to rare blood clots with low blood platelets

EMA

2021

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The ISTH Releases Interim Guidance on Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT)

ISTH

2021

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Laboratory testing for post ChAdOx1 nCOV-19 vaccination VITT: A challenge. Comment on: Recommendations for the clinical and laboratory diagnosis of VITT against COVID-19: Communication from the ISTH SSC Subcommittee on Platelet Immunology

ISTH SSC

2021

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Recommendations for the clinical and laboratory diagnosis of vaccine-induced immune thrombotic thrombocytopenia (VITT) for SARS-CoV-2 infections: Communication from the ISTH SSC Subcommittee on Platelet Immunology

ISTH SSC

2021

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Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT) Following Adenovirus Vector COVID-19 Vaccination: Interim Guidance for Healthcare Professionals in the Outpatient Setting

COVID-19 Advisory for Ontario

2021

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Recognizing, managing and reporting vaccineinduced immune thrombotic thrombocytopenia

2021

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Intensive Care guidance for the management of vaccine induced immune-thrombocytopenia and thrombosis (VITT)

UK Intensive Care Society and NACCS

2021

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The Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19: Molecular Diagnostic Testing

Infectious Diseases Society of America

2021

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ASH Guidelines on Use of Anticoagulation in Patients with COVID-19

ASH

2021

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The ADAMTS13-von Willebrand factor axis in COVID-19 patients

2021

View

A living WHO guideline on drugs to prevent covid-19

WHO

2021

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Thrombosis Canada Statement on Astrazeneca COVID-19 Vaccine and Thrombosis

Thrombosis Canada

2021

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ISTH Statement on Astrazeneca COVID-19 Vaccine and Thrombosis

ISTH

2021

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THROMBOSIS CANADA UPDATED STATEMENT ON ASTRAZENECA VACCINE AND BLOOD CLOTS - Thrombosis Canada seeks to reassure the public regarding blood clot risk and COVID-19 vaccines

Thrombosis Canada

2021

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Remdesivir for severe covid-19: a clinical practice guideline

BMJ Rapid Recommendation

2020

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IFCC Information Guide on COVID-19

IFCC

2020

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Thromboembolism and Anticoagulant Therapy During the COVID-19 Pandemic: Interim Clinical Guidance from the Anticoagulant Forum

Anticoagulant Forum

2020

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ISTH interim guidance on recognition and management of coagulopathy in COVID

ISTH

2020

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ISTH interim guidance on recognition and management of coagulopathy in COVID-19: A Comment

ISTH

2020

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ISTH interim guidance to recognition and management of coagulopathy in COVID-19

ISTH

2020

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Laboratory haemostasis monitoring in COVID-19

ISTH

2020

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Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19

Chinese Society on Thrombosis and Hemostasis

2020

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Practical guidance for the management of adults with Immune Thrombocytopenia during the COVID-19 pandemic

Reviewed by UK ITP Forum

2020

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Scientific and Standardization Committee Communication: Clinical Guidance on the Diagnosis, Prevention and Treatment of Venous Thromboembolism in Hospitalized Patients with COVID-19

ISTH SSC

2020

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Prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST Guideline and Expert Panel Report

CHEST

2020

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The need for accurate D-dimer reporting in COVID-19: Communication from the ISTH SSC on Fibrinolysis

ISTH SSC

2020

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COVID-19 and its implications for thrombosis and anticoagulation

ASH

2020

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A Systematic Approach for Managing Venous Thromboembolism in Patients with COVID-19

ISTH

2020

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Testing for SARS-CoV-2 (COVID-19): a systematic review and clinical guide to molecular and serological in-vitro diagnostic assays

2020

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Treatment of patients with nonsevere and severe coronavirus disease 2019: an evidence based guideline

2020

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Consensus-Based Clinical Recommendations and Research Priorities for Anticoagulant Thromboprophylaxis in Children Hospitalized for COVID-19 Related Illness

ISTH SSC

2020

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Management of the thrombotic risk associated with COVID-19: Guidance for the hemostasis laboratory

2020

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ISTH DIC subcommittee communication on anticoagulation in COVID-19

ISTH SSC

2020

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Quality of early evidence on the pathogenesis, diagnosis, prognosis and treatment of COVID-19

2020

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Venous Thromboembolism in COVID-19

2020

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Anticoagulation in COVID-19: Effect of Enoxaparin, Heparin, and Apixaban on Mortality

2020

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The hematology laboratory’s response to the COVID-19 pandemic: A scoping review

2020

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Thromboembolism risk of COVID-19 is high and associated with a higher risk of mortality: A systematic review and meta-analysis

2020

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Routine laboratory testing to determine if a patient has COVID-19

Cochrane COVID-19 Diagnostic Test Accuracy Group

2020

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Other

Guideline Title Organization Year Action

2022 ESC Guidelines on cardiovascular assessment and management of patients undergoing non-cardiac surgery: Developed by the task force for cardiovascular assessment and management of patients undergoing non-cardiac surgery of the European Society of Cardiology (ESC) Endorsed by the European Society of Anaesthesiology and Intensive Care (ESAIC)

ESC and endorsed by ESAIC

2022

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Thromboprophylaxis for venous thromboembolism prevention in hospitalized patients with cirrhosis: Guidance from the SSC of the ISTH

ISTH SSC

2022

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Perioperative Management of Antithrombotic Therapy: An American College of Chest Physicians Clinical Practice Guideline

CHEST

2022

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AGA Clinical Practice Update: Coagulation in Cirrhosis

AGA

2019

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Perioperative Management of Direct Oral Anticoagulants in Cardiac Surgery: Practice Recommendations Based on Current Evidence

2022

View

Use of factor concentrates for the management of perioperative bleeding: guidance from the SSC of the ISTH

ISTH SSC

2018/2019

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Consensus document of the Spanish Society of Digestives Diseases and the Spanish Society of Thrombosis and Haemostasis on massive nonvariceal gastrointestinal bleeding and direct-acting oral anticoagulants

Spanish Society of Digestives Diseases and Spanish Society of Thrombosis and Haemostasis

2022

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The clinical and laboratory diagnosis of vaccine-induced immune thrombotic thrombocytopenia

2022

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AANMCO position paper ‘Appropriateness of prescribing direct oral anticoagulants in stroke and systemic thromboembolism prevention in adult patients with non-valvular atrial fibrillation’

ANMCO

2022

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ANMCO position paper on antithrombotic treatment of patients with atrial fibrillation undergoing intracoronary stenting and/or acute coronary syndromes

ANMCO

2022

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2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association

AHA / ASA

2022

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Recommendations for standardized definitions, clinical assessment, and future research in pediatric clinically unsuspected venous thromboembolism: Communication from the ISTH SSC subcommittee on pediatric and neonatal thrombosis and hemostasis

ISTH SSC

2022

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Thromboembolic prevention and anticoagulant therapy during the COVID-19 pandemic: updated clinical guidance from the anticoagulation forum

Anticoagulant Forum

2022

View

Managing invasive procedures in haemophilia patients with limited resources, extended half-life concentrates or non-replacement therapies in 2022

2022

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Acquired haemophilia A: Italian Consensus Recommendations on diagnosis, general management and treatment of bleeding

AICE / SISET

2022

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Assessment and mitigation of bleeding risk in atrial fibrillation and venous thromboembolism: A Position Paper from the ESC Working Group on Thrombosis, in collaboration with the European Heart Rhythm Association, the Association for Acute Cardio Vascular Care and the Asia-Pacific Heart Rhythm Society

ESC Working Group on Thrombosis

2022

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Basic science research opportunities in thrombosis and hemostasis: Communication from the SSC of the ISTH

ISTH SSC

2022

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Bleeding disorders in implant dentistry: a narrative review and a treatment guide

2022

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American College of Gastroenterology-Canadian Association of Gastroenterology Clinical Practice Guideline: Management of Anticoagulants and Antiplatelets During Acute Gastrointestinal Bleeding and the Periendoscopic Period

American College of Gastroenterology and Canadian Association of Gastroenterology

2022

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Use and Prescription of Direct Oral Anticoagulants in Older and Frail Patients with Atrial Fibrillation: A Multidisciplinary Consensus Document

Multidisciplinary Consensus

2022

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European Renal Best Practice endorsement of guidelines for diagnosis and therapy of thrombotic thrombocytopenic purpura published by the International Society on Thrombosis and Haemostasis

European Renal Best Practice

2022

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Electronic diaries in the management of haemophilia gene therapy: Perspective of an expert group from the German, Austrian and Swiss Society on Thrombosis and Haemostasis (GTH)

German, Austrian and Swiss Society on Thrombosis and Haemostasis (GTH)

2022

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Management of DOAC in patients undergoing planned surgery or invasive procedure: FCSA position paper

FCSA

2021

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Periprocedural management of abnormal coagulation parameters and thrombocytopenia in patients with cirrhosis: Guidance from the SSC of the ISTH

ISTH SSC

2021

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European principles of care for women and girls with inherited bleeding disorders

European Association for Haemophilia and Allied Disorders

2021

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Strategies for the prevention and treatment of bleeding in patients treated with dabigatran: an update

2021

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Definition of a critical bleed in patients with immune thrombocytopenia: Communication from the ISTH SSC Subcommittee on Platelet Immunology

ISTH SSC

2021

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Use of direct oral anticoagulants in patients with obesity for treatment and prevention of venous thromboembolism: Updated communication from the ISTH SSC Subcommittee on Control of Anticoagulation

ISTH SSC

2021

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2021 Guidelines on the Diagnosis and Management of VWD

ASH, ISTH, NHF, WFH

2021

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2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation

European Heart Rhythm Association

2021

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Comment: 2021 European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation

2021

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Management of hemostatic complications in acute leukemia: Guidance from the SSC of the ISTH

ISTH SSC

2020

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A British Society for Haematology Guideline on the diagnosis and management of chronic myeloid leukaemia

BSH

2020

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2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association of Cardio-Thoracic Surgery (EACTS)

ECS

2020

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Standardizing Care to Manage Bleeding Disorders in Adolescents with Heavy Menses—A Joint Project from the ISTH Pediatric/Neonatal and Women's Health SSCs

ISTH SSC

2020

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WFH Guidelines for the Management of Hemophilia, 3rd edition

WFH

2020

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Investigation and management of erythrocytosi

2020

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Emergency management in patients with haemophilia A and inhibitors on prophylaxis with emicizumab: AICE practical guidance in collaboration with SIBioC, SIMEU, SIMEUP, SIPMeL and SISET

AICE

2020

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ISTH Guidelines for Treatment of Thrombotic Thrombocytopenic Purpura

ISTH

2020

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International Recommendations On The Diagnosis And Treatment Of Acquired Hemophilia A

2020

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Anticoagulant therapy for splanchnic vein thrombosis

ISTH SSC

2020

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Use of direct oral anticoagulants in patients with thrombotic antiphospholipid syndrome: Guidance from the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis

ISTH SSC

2020

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Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia

2020

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Good practice statements (GPS) for the clinical care of patients with thrombotic thrombocytopenic purpura

ISTH

2020

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American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism

ASH

2020

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Canadian stroke best practice recommendations: Management of Spontaneous Intracerebral Hemorrhage, 7th Edition Update 2020

Canadian Stroke Best Practice Recommendations (CSBPR)

2020

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2020 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants: A Report of the American College of Cardiology Solution Set Oversight Committee

ACC

2020

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EULAR recommendations for the management of antiphospholipid syndrome in adults

EULAR

2019

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Guidelines on the use of therapeutic apheresis in clinical practice - Evidence-based approach from the Writing Committee of the American Society for Apheresis: The Eighth Special Edition

American Society for Apheresis

2019

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McMaster RARE-Bestpractices clinical practice guideline on diagnosis and management of the catastrophic antiphospholipid syndrome

McMaster RARE-Bestpractices project group

2018

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European Myeloma Network recommendations on tools for the diagnosis and monitoring of multiple myeloma: what to use and when

European Myeloma Network

2018

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Review of the NICE guidelines for multiple myeloma

NCBI

2017

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Acquired hemophilia A: Updated review of evidence and treatment guidance.

HTRS

2017

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Guideline for the diagnosis and management of the rare coagulation disorders.  A United Kingdom Haemophilia Centre Doctors’ Organization guideline on behalf of the British Committee for Standards in Haematology

UKHCDO / BCSH

2014

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Patient self-testing and self-management oforal anticoagulant with vitamin K antagonists: guidance from the British Committee for Standards in Haematology

BCSH

2014

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Diagnosis and management of acquired coagulation inhibitors: a guideline form UKHCDO

UKHCDO / BCSH

2013

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Diagnosis and treatment of factor VIII and IX inhibitors in congenital haemophilia: (4th edition)

UKHCDO / BCSH

2013

View

WFH Guidelines for the Management of Hemophilia, 2nd edition

WFH

2012

View

Post-analytical

Guideline Title Organization Year Action

A new hemophilia carrier nomenclature to define hemophilia in women and girls: Communication from the SSC of the ISTH

ISTH SSC

2021

View

American Society of Hematology 2021 guidelines for management of venous thromboembolism: prevention and treatment in patients with cancer

ASH

2021

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International Council for Standardization in Haematology Recommendations for Hemostasis Critical Values, Tests, and Reporting

ICSH

2020

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Comprehensive review of the impact of direct oral anticoagulants on thrombophilia diagnostic tests: Practical recommendations for the laboratory

2020

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Guideline Papers

ICSH

2021

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Recommendations on the Standardization of Critical Results in Hematology – Adult Population

ICSH

2016

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Guideline Papers

BSH

2021

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