Symposium Program

ISLH 2023 educational content
Corporate Symposia

ISLH is happy to present the 2023 Corporate Symposium. Please note the following:

  • Each event is planned independently of the ISLH program committee and ISLH does not endorse the programming content.
  • You must be an ISLH registrant in order to attend any satellite symposia.
  • There is no cost to attend these symposia.
  • All symposia occur during a meal and food will be provided.
  • All admittance will be on a first-come, first-served basis.


Thursday, May 11

Title: Faster than Glass: Implications and Outcomes of Fully Digital Pathology

Sponsored By: Siemens

12:30 - 1:30 PM, Galerie 1-3
The switch to digital pathology is imminent as it will allow clinicians to make better decisions and ultimately, improve the health of patients. Dr. Giovanni Lujan will share his experience on implementing a fully digital sign out at a major academic medical center that has been fully digital for over three years. This session will identify the components for a successful transition into a digital workflow, mostly from a pathologist perspective, including change management and demystification of the actual workflow. The focus will be on the technical aspects of having no glass and no paper, just the computer screen; and will walk through all the advantages as well as those disadvantages, either real or perceived, that pathologists are concerned about.

Dr. Giovanni Lujan
The Ohio State University

Lab Developed Test Validation for a Qualitative and Semi-quantitative Flow Cytometric Assay: PNH Testing Example

Sponsored By: Sysmex
12:30 - 1:30 PM, Galerie 4-6

Method validation and quality control is required for all non-waived clinical tests in regulated laboratory environments. Flow cytometry assays, unlike traditional soluble analyte assays, have unique requirements for validation and verification of qualitative and semi-quantitative assays. This session will highlight one laboratory’s challenging journey to validate a diagnostic panel for paroxysmal nocturnal hemoglobinemia (PNH) using the ICCS/ESCCA PNH consensus Guidelines as well as the recently published CLSI H62 Guidelines. The speaker will share her lab’s experience with validating and maintaining quality control for clinical flow cytometry assays. Case studies will be used to illustrate the process.

Andrea Illingworth, MS, SCYM CM
Dahl-Chase Diagnostic Services, Bangor, ME

Friday, May 12

The Tails and Trails of Bone Marrow Aspirate Differentials

Hosted by: Cellavision
12:30 - 1:30 PM, Galerie 1-3

The bone marrow nucleated cell differential is an essential component of the diagnostic workup of hematological abnormalities. Selection of the areas on the aspirate slide where the nucleated cell differential is counted is critical for obtaining accurate cell count results. However, guidance on how areas should be selected is limited and there are no investigations in the literature on how area selection can affect the nucleated differential cell count. This presentation reviews how area selection on bone marrow aspirate slides can impact the results of the nucleated cell differential and how the use of artificial intelligence and digital cell morphology can potentially aid the selection of analysis areas in an objective manner.

Dr. Steve Marionneaux
Scientific Affairs, CellaVision AB,
Lund, Sweden

Chasing ghosts: automating the Kleihauer-Betke test using artificial intelligence

Acid elution techniques using the Kleihauer-Betke method are still commonly employed in transfusion laboratories for estimation of feto-maternal hemorrhage due to its low cost and accessibility. This talk is going to highlight the pitfalls of the technique and present the results of a research project on how artificial intelligence in combination with the CellaVision® DC-1 Digital Morphology Analyzer offers a feasible approach to standardize, automate and increase the precision of FMH estimation using Kleihauer-Betke smears.

Marlene Correia
Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK

Automated Image Analysis in Support of Anti-Malarial Drug Development

Malaria remains the greatest single agent killer of children on the planet and the death toll has risen in recent years in part due to the spread of drug-resistant parasites. New drugs are required, and drug discovery programs require high accuracy quantification of parasitemia on thousands of blood films. Because of this need for high throughput quantification, we have capitalized on a research use only automated image analysis software using the CellaVision DM9600 digital morphology analyzer to quantify and archive this critical data. We will present the results of our drug discovery program with emphasis on the enabling role of automated quantification of parasitemia.

Dr. Jonathan D. Kurtis
Center for International Health Research, Rhode Island Hospital, Brown University Medical School, Providence, RI, USA

Introduction to Alinity H-Series Scatterplots from Interesting Case Studies

Sponsored By: Abbott
12:30 - 1:30 PM, Galerie 4-6

We will take a deep dive into how the advanced Multi-Angle Polarized Scatter Separation (MAPSS™) technology generates scatterplots with bountiful data in differentiating hematopoietic diseases. Changes can be seen in myelodysplastic syndrome, sickle cell disease, dengue, malaria and much more. Be sure to visit us at Booth #203 to learn more about the Hematology solutions from Abbott and the unique technology of the Alinity h-series system.
Disclaimer: Product in development. Alinity hq is a Class I laser product. The Alinity h-series is available in select countries, not including the United States.

Christine Rongey, M.D.
Director of Scientific and Medical Affairs, Abbott

Click Here to Register for the Abbott Workshop

Saturday, May 13

Integrated Quality Management for Digital morphology analyzers: challenges of the IVDR for Laboratories in Hematology and oncology following ISO 15189 requirements

Sponsored By: West Medica
12:00 - 1:00 PM, Galerie 1-3

The MDR /IVDR EU Regulation had changed the world for the medical devices manufacturers and created a real struggle in time, resources and know-how management. For the laboratories it brought silently a huge change. “Is that a “in house production”? is that a Lab developed test, how can I validate this? “ These are the questions arising in each laboratory, that not all IVD manufacturers can reply. The challenges are connected especially with new technologies like digital imaging, AI applications, rapid on-site evaluation (ROSE) and the definitions of those technologies which are worldwide still not unified. The main point remains – in a world where qualified human resources are still challenging - how laboratories can request/ expect from IVD solutions to provide a global support. The impact of Quality management on the diagnostic process shall be improved and integrated in the workflow of IVD devices global environment. This workshop presents insights how cooperation, laboratory, users needs and manufacturers should be analyzed under Quality management views to create environment securing correct diagnosis under a manageable life routine for laboratories without creating more paper work.

Mag. Marie Salin
TÜV Austria certified auditor for Medical products and Laboratories
Product development at West Medica, Austria.

Mag. Ingrid Brezaniova
PhD, clinical Head at West Medica, Austria

Full-Field Digital Peripheral Blood and Bone Marrow Analysis: Innovation Meets Real-World Practice

Sponsored By: Scopio Labs
12:00 - 1:00 PM, Galerie 4-6

Work volumes and staff shortages pose significant challenges to lab operations. Manual blood differentials (100-200 cells) and bone marrow differentials (currently n=500) remain a key contributing factor, because they are time-consuming and require morphological expertise on premises. Many hospitals and laboratory service providers find themselves forgoing morphology expertise during nights and weekends, instead sending samples out for review, creating operational burdens and the potential for delaying care.

This symposium provides evidence-based validation of a full-field peripheral blood smear workflow solution in a laboratory service provider setting. In addition, it examines the workflow implications of a full-field bone marrow solution in a community hospital network. The speakers will share their experiences with full-field digital cell morphology, AI-supported workflows, and remote reviews that eliminate the need for manual microscopy. They will also discuss the technology’s importance given the latest WHO/ICC classification guidelines.

Professor Rajan Dewar, MD, PhD
Vice Chair, Department of Pathology, New York Medical College & Westchester Medical Center, NY

Joyce Richardson
Senior Biomedical Scientist, Dept. of Haematology and Special Haematology, Zentrum für Labormedizin (ZLM), St. Gallen, Switzerland