International Society for Laboratory Hematology

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Inventory of Guidelines

ISLH is committed to ensuring an up to date inventory of guidelines that support the Hematology Laboratory community. To this end, below are additional guidelines.

Pre-analytical
Optimal Testing: AACC’s Guide to Lab Test Utilization	AACC	2020	View
Guidelines on the laboratory aspects of assays used in haemostasis and thrombosis	BSH	2020	View
Strategies for eliciting and synthesizing evidence for guidelines in rare diseases	BMC	2019	View
Reversal of direct oral anticoagulants: Guidance from the Anticoagulation Forum	Anticoagulation Forum	2019	View
Croatian Society of Medical Biochemistry and Laboratory Medicine: National recommendations for blood collection, processing, performance and reporting of results for coagulation screening assays prothrombin time, activated partial thromboplastin time, thrombin time, fibrinogen and D-dimer.	Croatian Society of Medical Biochemistry and Laboratory Medicine	2019	View
Joint EFLM-COLABIOCLI Recommendation for venous blood sampling	EFLM-COLABIOCLI	2018	View
Hematopathology
Nucleic acid amplification assays for molecular hematopathology: Approved Guideline – second edition	CLSI (this is now listed as a hematology document)	2012	View
Coagulation
Recommendations for clinical laboratory testing of activated protein C resistance; communication from the SSC of the ISTH	ISTH / SSC	2019	View
Internal quality control practices in coagulation laboratories: recommendations based on a patterns-of-practice survey	IQMH	2015	View Additional Information
Diagnosis of inherited platelet function disorders: guidance from the SSC of the ISTH	ISTH	2015	View
Testing for antiphospholipid antibodies with solid phase assays: guidance from the SSC of the ISTH	ISTH	2014	View
Validation of hemostasis and coagulation assays: recommendations and guidelines	Independent authors (STH)	2014	View Additional Information
The diagnosis and management of von Willebrand disease: a United Kingdom Haemophilia Centre Doctors Organization guideline approved by the British Committee for Standards in Haematology	UKHCDO / BCSH	2014	View
European evidence-based recommendations for diagnosis and treatment of paediatric antiphospholipid syndrome: the SHARE initiative	NIH	2017	View
Activated Partial Thromboplastin Time Monitoring of Unfractionated Heparin Therapy: Issues and Recommendations	NIH	2017	View
Position Paper on laboratory testing for patients on direct oral anticoagulants. A Consensus Document from the SISET, FCSA, SIBioC and SIPMeL	Blood Transfusion	2017	View
International Council for Standardization in Haematology (ICSH) Recommendations for Laboratory Measurement of Direct Oral Anticoagulants	ICSH	2018	View
Laboratory criteria for antiphospholipid syndrome: communication from the SSC of the ISTH	ISTH SSC	2018	View
Lupus anticoagulant detection in anticoagulated patients. Guidance from the Scientific and Standardization Committee for lupus anticoagulant/antiphospholipid antibodies of the International Society on Thrombosis and Haemostasis	ISTH SSC	2020	View
Guidance from the Scientific and Standardization Committee for lupus anticoagulant/antiphospholipid antibodies of the International Society on Thrombosis and Haemostasis	ISTH SSC	2020	View
Update of the guidelines for lupus anticoagulant detection and interpretation	ISTH SSC	2020	View
Recommendations for clinical laboratory testing for protein C deficiency, for the subcommittee on plasma coagulation inhibitors of the ISTH	ISTH SSC	2020	View
Recommendations for clinical laboratory testing for protein S deficiency: Communication from the SSC committee plasma coagulation inhibitors of the ISTH	ISTH SSC	2021	View
Hemoglobinopathies and other red cell disorders
ICSH recommendations for assessing automated high-performance liquid chromatography and capillary electrophoresis equipment for the quantitation of HbA2	ICSH	2015	View
ICSH guidelines for the laboratory diagnosis of nonimmune hereditary red cell membrane disorders Supporting information	ICSH	2015	View Additional Information
ICSH recommendations for identification, diagnostic value, and quantitation of schistocytes	ICSH	2011	View
ICSH recommendations for identification, diagnostic value, and quantitation of schistocytes	ICSH	2011	View
Cellular analysis, including peripheral blood, bone marrow and body fluid analysis
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.	WHO	2016	View
ICSH recommendations for the standardization of nomenclature and grading of peripheral blood cell morphological features Supporting information	ICSH	2015	View Additional Information
ICSH guidelines for the standardization of bone marrow immunohistochemistry	ICSH	2015	View
ICSH guidelines for the evaluation of blood cell analyzers including those used for differential leucocyte and reticulocyte counting	ICSH	2014	View
ICSH guidelines for the verification and performance of automated cell counters for body fluids	ICSH	2014	View
Initial Diagnostic Workup of Acute Leukemia: Guideline From the College of American Pathologists and the American Society of Hematology	CAP	2016	View
Flow Cytometry
Immunophenotyping of acute leukemia and lymphoproliferative disorders: a consensus proposal of the European LeukemiaNet Work package 10	ESCCA	2011	View Additional Information
Minimal Residual Disease and Childhood Leukemia: Standard of Care Recommendations From the Pediatric Oncology Group of Ontario MRD Working Group	PBC	2016	View
ICCS/ESCCA consensus guidelines to detect GPI-deficient cells in paroxysmal nocturnal hemoglobinuria (PNH) and related disorders Part 1 – clinical utility Part 2 – reagent selection and assay optimization for high-sensitivity testing Part 3 – data analysis, reporting and case studies Part 4 – assay validation and quality assurance	ICCS/ESCCA	2018	View

The following guidelines are not restricted to laboratory testing:

A British Society for Haematology Guideline on the diagnosis and management of chronic myeloid leukaemia	BSH	2020	View
2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association of Cardio-Thoracic Surgery (EACTS)	ECS	2020	View
Standardizing Care to Manage Bleeding Disorders in Adolescents with Heavy Menses—A Joint Project from the ISTH Pediatric/Neonatal and Women's Health SSCs	ISTH SSC	2020	View
WFH Guidelines for the Management of Hemophilia, 3rd edition	WFH	2020	View
Investigation and management of erythrocytosis		2020	View
Guideline for the diagnosis and management of the rare coagulation disorders. A United Kingdom Haemophilia Centre Doctors’ Organization guideline on behalf of the British Committee for Standards in Haematology	UKHCDO / BCSH	2014	View
Patient self-testing and self-management oforal anticoagulant with vitamin K antagonists: guidance from the British Committee for Standards in Haematology	BCSH	2014	View
Diagnosis and management of acquired coagulation inhibitors: a guideline form UKHCDO	UKHCDO / BCSH	2013	View
Diagnosis and treatment of factor VIII and IX inhibitors in congenital haemophilia: (4th edition)	UKHCDO / BCSH	2013	View
Review of the NICE guidelines for multiple myeloma	NCBI	2017	View
WFH Guidelines for the Management of Hemophilia, 2nd edition	WFH	2012	View
McMaster RARE-Bestpractices clinical practice guideline on diagnosis and management of the catastrophic antiphospholipid syndrome	McMaster RARE-Bestpractices project group	2018	View
European Myeloma Network recommendations on tools for the diagnosis and monitoring of multiple myeloma: what to use and when	European Myeloma Network	2018	View
EULAR recommendations for the management of antiphospholipid syndrome in adults	EULAR	2019	View
Guidelines on the use of therapeutic apheresis in clinical practice - Evidence-based approach from the Writing Committee of the American Society for Apheresis: The Eighth Special Edition	American Society for Apheresis	2019	View
Acquired hemophilia A: Updated review of evidence and treatment guidance.	Hemostasis and Thrombosis Research Society of North America (HTRS)	2017	View
Emergency management in patients with haemophilia A and inhibitors on prophylaxis with emicizumab: AICE practical guidance in collaboration with SIBioC, SIMEU, SIMEUP, SIPMeL and SISET	AICE	2020	View
ISTH Guidelines for Treatment of Thrombotic Thrombocytopenic Purpura	ISTH	2020	View
International Recommendations On The Diagnosis And Treatment Of Acquired Hemophilia A		2020	View
Anticoagulant therapy for splanchnic vein thrombosis	ISTH SSC	2020	View
Use of direct oral anticoagulants in patients with thrombotic antiphospholipid syndrome: Guidance from the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis	ISTH SSC	2020	View
Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia		2020	View
Good practice statements (GPS) for the clinical care of patients with thrombotic thrombocytopenic purpura	ISTH	2020	View
American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism	ASH	2020	View
Canadian stroke best practice recommendations: Management of Spontaneous Intracerebral Hemorrhage, 7th Edition Update 2020	Canadian Stroke Best Practice Recommendations (CSBPR)	2020	View
2020 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants: A Report of the American College of Cardiology Solution Set Oversight Committee	ACC	2020	View
2021 Guidelines on the Diagnosis and Management of VWD	ASH, ISTH, NHF, WFH	2021	View
Management of hemostatic complications in acute leukemia: Guidance from the SSC of the ISTH	ISTH SSC	2020	View
Post-analytical
Recommendations on the Standardization of Critical Results in Hematology – Adult Population	ICSH	2016	View
Guideline Papers	ICSH	2018	View
Guideline Papers	BSH	2016	View
International Council for Standardization in Haematology Recommendations for Hemostasis Critical Values, Tests, and Reporting	ICSH	2020	View
Comprehensive review of the impact of direct oral anticoagulants on thrombophilia diagnostic tests: Practical recommendations for the laboratory		2020	View
American Society of Hematology 2021 guidelines for management of venous thromboembolism: prevention and treatment in patients with cancer	ASH	2021	View
Coagulopathy and Hematology Guidance related to COVID-19 Disclaimer: COVID-19 research and publications is rapidly evolving. ISLH will strive to have the most up-to-date resources available however there may be some delay in posting.
Remdesivir for severe covid-19: a clinical practice guideline	BMJ Rapid Recommendation	2020	View
IFCC Information Guide on COVID-19	IFCC	2020	View
Thromboembolism and Anticoagulant Therapy During the COVID-19 Pandemic: Interim Clinical Guidance from the Anticoagulant Forum	Anticoagulant Forum	2020	View
ISTH interim guidance on recognition and management of coagulopathy in COVID- ADDENDUMS to above publication: ISTH interim guidance on recognition and management of coagulopathy in COVID-19: A Comment ISTH interim guidance to recognition and management of coagulopathy in COVID-19 Laboratory haemostasis monitoring in COVID-19	ISTH	2020	View View View View
Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19	Chinese Society on Thrombosis and Hemostasis	2020	View
Practical guidance for the management of adults with Immune Thrombocytopenia during the COVID-19 pandemic	Reviewed by UK ITP Forum	2020	View
Scientific and Standardization Committee Communication: Clinical Guidance on the Diagnosis, Prevention and Treatment of Venous Thromboembolism in Hospitalized Patients with COVID-19	ISTH SSC	2020	View
Prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST Guideline and Expert Panel Report	CHEST	2020	View
The need for accurate D-dimer reporting in COVID-19: Communication from the ISTH SSC on Fibrinolysis	ISTH SSC	2020	View
COVID-19 and its implications for thrombosis and anticoagulation	ASH	2020	View
A Systematic Approach for Managing Venous Thromboembolism in Patients with COVID-19 - International Society on Thrombosis and Haemostasis, Inc.	ISTH	2020	View
Testing for SARS-CoV-2 (COVID-19): a systematic review and clinical guide to molecular and serological in-vitro diagnostic assays		2020	View
Treatment of patients with nonsevere and severe coronavirus disease 2019: an evidence based guideline		2020	View
Consensus-Based Clinical Recommendations and Research Priorities for Anticoagulant Thromboprophylaxis in Children Hospitalized for COVID-19 Related Illness	ISTH SSC	2020	View
Management of the thrombotic risk associated with COVID-19: Guidance for the hemostasis laboratory		2020	View
ISTH DIC subcommittee communication on anticoagulation in COVID-19	ISTH SSC	2020	View
Quality of early evidence on the pathogenesis, diagnosis, prognosis and treatment of COVID-19		2020	View
Venous Thromboembolism in COVID-19		2020	View
Anticoagulation in COVID-19: Effect of Enoxaparin, Heparin, and Apixaban on Mortality		2020	View
The hematology laboratory’s response to the COVID-19 pandemic: A scoping review		2020	View
Thromboembolism risk of COVID-19 is high and associated with a higher risk of mortality: A systematic review and meta-analysis		2020	View
Routine laboratory testing to determine if a patient has COVID-19	Cochrane COVID-19 Diagnostic Test Accuracy Group	2020	View
The Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19: Molecular Diagnostic Testing	Infectious Diseases Society of America	2021	View
ASH Guidelines on Use of Anticoagulation in Patients with COVID-19	ASH	2021	View
The ADAMTS13-von Willebrand factor axis in COVID-19 patients		2021	View
A living WHO guideline on drugs to prevent covid-19	WHO	2021	View
Thrombosis Canada Statement on Astrazeneca COVID-19 Vaccine and Thrombosis	Thrombosis Canada	2021	View
ISTH Statement on Astrazeneca COVID-19 Vaccine and Thrombosis	ISTH	2021	View
THROMBOSIS CANADA UPDATED STATEMENT ON ASTRAZENECA VACCINE AND BLOOD CLOTS Thrombosis Canada seeks to reassure the public regarding blood clot risk and COVID-19 vaccines	Thrombosis Canada	2021	View
COVID-19 Vaccine AstraZeneca: benefits still outweigh the risks despite possible link to rare blood clots with low blood platelets	European Medicines Agency (EMA)	2021	View

Inventory of Guidelines

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